Hígado graso no alcohólico asociado a síndrome metabólico

Authors

DOI:

https://doi.org/10.46780/cunzac.v5i2.78

Keywords:

fatty liver, metabolic syndrome, internal medicine

Abstract

OBJECTIVE: to describe the association between nonalcoholic fatty liver and metabolic syndrome. METHODOLOGY: a precise and coherent review of bibliographies based on primary and secondary sources that included updated information was carried out. RESULTS: nonalcoholic fatty liver is associated with metabolic syndrome, through its main trigger, which is obesity. Therefore, the risk factors for the development of non-alcoholic fatty liver are insulin resistance, dyslipidemia and arterial hypertension, correlating with the degree of fatty infiltration. The pathophysiology of liver disease is linked to the pathogenesis of the metabolic syndrome, having a synergistic effect between pro-inflammatory mediators that are secreted by adipokines such as interleukin-6 and tumor necrosis factor alpha. These cytokines cause alterations in the hepatocyte, increasing the process of fat infiltration and degree of fibrosis, allowing the appearance of this entity. Complications of developing this liver disease are atherosclerosis, cerebrovascular events, nonalcoholic steatohepatitis, liver cirrhosis, and hepatocarcinoma. CONCLUSION: nonalcoholic liver disease as it progresses through its different stages allows increased mortality in patients with metabolic syndrome.

Downloads

Download data is not yet available.

Author Biography

Carlos Estuardo Hurtado Rodríguez, Universidad de San Carlos de Guatemala

He is a Physician and Surgeon from the University of San Carlos de Guatemala. He has conducted research on Internal Medicine, Surgery, Gynecology, Pediatrics during supervised hospital professional practice. Currently, he works as a shift doctor in the private sector.

References

Almarza, J. (2010). Hígado graso no alcohólico: ¿un componente inflamatorio del síndrome metabólico?. Perspectivas en Nutrición Humana, 12(2), 164-175. http://www.scielo.org.co/pdf/penh/v12n2/v12n2a5.pdf

Brodersen, C. E., Tallis, S. y Perazzo, J. C. (2010). Esteatosis y esteatohepatitis, fisiopatología y su interacción con el virus C. FEPREVA, 3(2), 22-40. http://www.fepreva.org/curso/4to_curso/bibliografia/volumen3/vol_3_2.pdf

Delgado, H. M., García, F. I. y García, I. (2018). La enfermedad por hígado graso no alcohólico y el trabajo del internista. Revista del Hospital Juárez de México, 85(2), 86-93. https://www.medigraphic.com/pdfs/juarez/ju-2018/ju182e.pdf

Freÿre, M. J. (2019). Hígado graso no alcohólico y síndrome metabólico. México, MED-CMC. https://med-cmc.com/higado-graso-no-alcoholico-y-sindrome-metabolico/

Martín, V., González, R., Mendoza, J., García, L. y Moreno, R. (2013). Etiopatogenia, diagnóstico y tratamiento de la enfermedad del hígado graso no alcohólica. Revista Española de Enfermedades Digestivas, 105(7), 409-420. https://scielo.isciii.es/pdf/diges/v105n7/es_punto_vista.pdf

Méndez, N., Gutiérrez, Y., Chávez, N. C., Kobashi, R. A. y Uribe, M. (2010). Hígado graso no alcohólico y esteatohepatitis no alcohólica: conceptos actuales. Revista de Gastroenterología de México, 75(s2), 143-148. http://www.revistagastroenterologiamexico.org/es-pdf-X0375090610873768

Pineda, M. G., Benítez, A., Figueredo, R., Ayala, F. y Arguello, R. (2017). Frecuencia de hígado graso no alcohólico diagnosticado por ecografía abdominal en pacientes obesos. Anales de la Facultad de Ciencias Médicas, 50(2), 35-50. http://scielo.iics.una.py/pdf/anales/v50n2/1816-8949-anales-50-02-00035.pdf DOI: https://doi.org/10.18004/anales/2017.050(02)35-050

Pinto, C., Pinchemel, H. y Arrese, M. (2019). Factores de riesgo de la enfermedad por hígado graso no alcohólico en poblaciones de Latinoamérica: situación actual y perspectivas. Clinical Liver Disease, 13(s1), s5-s8. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541043/pdf/CLD-13-S5.pdf DOI: https://doi.org/10.1002/cld.837

Sahuquillo, A. (2017). Esteatosis hepática no alcohólica en pacientes con síndrome metabólico. Tesis Dr. Madrid, España, Universidad Autónoma de Madrid, 80 p. https://repositorio.uam.es/bitstream/handle/10486/681344/sahuquillo_martinez_alicia.pdf?sequence=1

Serradilla, M., Oliver, J. R., Palomares, A. y Ramia, J. M. (2020). Síndrome metabólico, enfermedad hepática grasa no alcohólica y hepatocarcinoma. Revista Española de Enfermedades Digestivas, 112(2), 133-138. https://medes.com/publication/151152 DOI: https://doi.org/10.17235/reed.2020.6640/2019

Published

2022-08-26

How to Cite

Hurtado Rodríguez, C. E. . (2022). Hígado graso no alcohólico asociado a síndrome metabólico. Revista Académica CUNZAC, 5(2), 115–121. https://doi.org/10.46780/cunzac.v5i2.78

Issue

Section

Ensayos científicos